Interleukin 12: Basic Biology and Potential Applications in Cancer Treatment
نویسندگان
چکیده
منابع مشابه
Interleukin 12 in cancer treatment.
Interleukin 12 (IL-12) is made up of two disulphidelinked chains, p35 and p40. The cytokine is produced by monocytes, macrophages, myeloid dendritic cells and B cells. It stimulates development of NK cells and TH1 differentiation of CD4 T cells, thus participating in the regulation of the immune response (for a review, see Klein and Hořejší, 1997; Grufman and Kärre, 2000; Jinushi and Tahara, 20...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 1996
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.1-1-88